GIST News A Wave of Information By the LIFE RAFT GROUP

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January 2007

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  • Overcoming treatment resistance in GIST patients by Jonathan Fletcher, M.D. The major challenge in confronting imatinib (and sunitinib) resistance mutations clinically is the apparent heterogeneity of such mutations that can be identified amongst individual GIST patients.
  • Questions to consider for adjuvant treatment by Jerry Call GIST patients face many decisions about their treatment. Many GIST patients have surgery to remove a primary tumor and do not have detectable metastases at the time of surgery. This large group of patients faces the decision of whether or not to take Gleevec to try to prevent or delay a recurrence.
  • Finding a silver-lining when living with cancer by Erin Kristoff Rachel Tate is very excited about a new change in her life. She is about to move into a new house that has a studio. Why is this so important? Because Rachel will have a new space to do her favorite activity with her sister, both of whom love the art of silversmithing
  • January 2007 clinical trial updates by Jim Hughes