Young Adult GIST Data

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Reports - All under 30 | Carney's Triad | Pediatric GIST (under 18) | 18 to 24 years old | 25 to 30 years old

Life Raft Group Data

GIST in young adults may be similar or quite different than pediatric GIST (under 18) as the disease tends to transition from the pediatric type to the adult type. GISTs from patients in this age range may have wild-type GIST (and be more similiar to pediatric GIST), or they may have GISTs with KIT or PDGRA mutations and be more similar to adult GISTs. The response to treatment and the natural course of the disease may vary considerably as well.

**GIST in young adults, 18 to 24**
Patient ID	Gender	Misdiagnosed Gist?	Original Cancer Diagnosis	Age at diagnosis	Current age	Years living w/GIST	GIST Type	Mutation	Location of Primary Tumor at Diagnosis	Current Treatment
PG-117	F	TRUE	Other	19.2	32.2	12.9	GIST		Stomach	Gleevec 400 mg
PG-139	F	FALSE		19.5	21.1	1.6	GIST		Stomach	Neoadjuvant Gleevec 800 mg
PG-100	F	FALSE		19.6	23.3	3.7	GIST		Stomach	None
PG-138	F	TRUE	Other	19.9	34.5	14.6	GIST	Wildtype	Stomach	Sutent 31.5 mg (Alternates 37.5 & 25)
PG-108	F	TRUE	Other	20.3	29.0	8.7	GIST		Small Bowel	None, NED
PG-102	F	FALSE		20.6	25.4 at death	5.2	GIST		Stomach	Deceased
PG-105	F	FALSE		21.0	25.5	4.5	GIST	Wildtype	Stomach	Sutent 50 mg 4/2 schedule
PG-130	F	FALSE		21.1	21.8	0.6	GIST		Stomach	Gleevec
PG-149	F	FALSE		22.6	25.7 at death	3.1	GIST		Stomach	Deceased
PG-147	F	TRUE	LMS	23.7	38.0 at death	14.3	GIST	Kit exon 11	Stomach	Deceased
PG-135	M	FALSE		18.0	19.6	1.6	GIST	Wildtype	Stomach	None, NED
PG-118	M	FALSE		19.3	22.3	3.1	GIST		Stomach	none, finished adjuvant Gleevec (1 yr)
PG-126	M	FALSE		21.8	23.0	1.2	GIST		Small Bowel	Gleevec 400 mg adjuvant
PG-116	M	FALSE		23.1	24.9 at death	1.7	GIST		Liver	Deceased
PG-128	M	FALSE		23.9	27.7	3.8	GIST		Stomach	Gleevec + Rapamycin
PG-157	M			?	23 at death	?	GIST			Deceased

This pediatric portion of the website is dedicated to the memory of Jonathan Montague

1. Gastrointestinal Stromal Tumors in Children and Young Adults.
A Clinicopathologic, Molecular, and Genomic Study of 15 Cases and Review of the Literature. J Pediatr Hematol Oncol Volume 27, Number 4, April 2005. Sonam Prakash, MD, Lisa Sarran, MS, Nicholas Socci, PhD, Ronald P. DeMatteo, MD, Jonathan Eisenstat, MD, Alba M. Greco, MD,
Robert G. Maki, MD, PhD,{ Leonard H. Wexler, MD,k Michael P. LaQuaglia, MD, Peter Besmer, PhD, and Cristina R. Antonescu, MD